CC Cardiol Croat Cardiologia Croatica Cardiol. Croat. 1848-543X 1848-5448 Croatian Cardiac Society CC_2014_9_3-4_86 10.15836/ccar.2014.86 Extended Abstract Exercise testing to stratify risk in asymptomatic moderate and severe aortic stenosis KusljugicZumreta1BarakovicFahir1Dizdarevic-HudicLarisa1DilicMirza2SmajicElnur1AvdagicMelika1Kovacevic-DivkovicKatarina1BijedicAmira1 University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina Correspondence to Zumreta Kusljugic, Javna zdravstvena ustanova Univerzitetski klinicki centar Tuzla, Trnovac bb, 75 000 Tuzla, Bosnia and Herzegovina; Phone: +387-35-303-500; E-mail: zumreta.kusljugic@ukctuzla.ba 032014 032014 9 3-4 86 86 Croatian Cardiac Society 2014 Croatian Cardiac Society KEYWORDS: asymptomatic aortic stenosistreadmill stress testingprognosis

Introduction: The literature contains various data regarding the value of the exercise testing in patients with asymptomatic aortic stenosis (AS). The aim: To determine the importance of exercise testing in cardiovascular risk stratification in patients with moderate severe to severe aortic stenosis.

Methods and Results: Out of a total 33 patients with moderate severe to severe asymptomatic aortic stenosis (mean aortic area EOA 0.9±0.34 cm2) we followed up 31 patients (two were excluded) during the 12 months’ period by clinical, transthoracic echocardiogram and treadmill stress testing. 18 (58%) patients discontinued the test due to limiting symptoms, and had severe aortic stenosis (EOA ≤0.8 cm2). During the follow-up, 11 patients spontaneously developed severe symptoms within 12 months’ period, of whom 8 underwent aortic valve replacement, one patient died (sudden cardiac death), and two patients had a stroke. A total of 20 patients remained free of any symptoms. The highest predictive value is EOA ≤0.8 cm2 for the provoked symptom test and it is 85%. ST depression had the highest negative predictive value.

Conclusion: Only limiting symptoms with critical aortic of area (EOA ≤0.8 cm2) have a positive predictive value.